Thursday 22 March 2012

Propionibacterium Acnes-Infectious Diseases-Pathogenic Strains-Genetic Diversity

Genetic diversity of Propionibacterium acnes strains isolated from human skin in Japan and comparison with their distribution in Europe.

Authors: Dekio I, Rajendram D, Morita E, Gharbia S, Shah HN Abstract Propionibacterium acnes, a commensal of human skin, is also an opportunistic pathogen of common acne and other infectious diseases. However, it is still not obvious which strain is pathogenic for a certain infectious diseases, and investigations to characterise pathogenic strains using molecular typing methods such as multilocus sequence typing (MLST) using several housekeeping genes has been in progress. However, to date, such analysis has focused mainly on strains isolated from Europeans, and it is unclear whether the clonal distribution in other parts of the world is similar. Here, we analysed 50 strains of P. acnes from healthy humans and patients with atopic dermatitis (AD) in Japan and utilised MLST of seven... read more..

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